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NEWS Release

WEX Reports Year End Financial Results

Date: June 29, 2005

Toronto Stock Exchange Trading Symbol: WXI
http://www.wexpharma.com
E-mail: wex@wexpharma.com

Vancouver, BC (June 29, 2005) - WEX Pharmaceuticals Inc. ("WEX" or the "Company”) reported today highlights and financial results for the fiscal year ended March 31, 2005.  All amounts, unless specified otherwise, are in Canadian dollars.

For the year ended March 31, 2005, the Company recorded a loss of $11.7 million ($0.35 per common share) compared to a loss of $8.0 million ($0.31 per common share) for the year ended March 31, 2004.  The increase in loss for the year ended March 31, 2005, when compared to the preceding year, is attributable to substantial increases in research and development costs as they relate to the clinical trials of Tectin™ and Tetrodin™.  The Company expects losses to continue during the next few years as it continues to focus resources on clinical trials in an effort to further the commercialization of Tectin™.

 

The Company raised a net $6.8 million (US$5.1million) in proceeds from debentures issued in the year ended March 31, 2005 and had cash, cash equivalents and short term investments of $20.8 million at the end of the year as compared to $18.3 million as at March 31, 2004.  Not included in the $20.8 million was a payment from Laboratories del Dr. Esteve, S.A.("Esteve") of approximately $3.1 million (€2 million), which was included in accounts receivable as at March 31, 2005, but subsequently received.   

 

The Company’s subsidiary in China, Nanning Maple Leaf Pharmaceuticals Co. Ltd. (“NMLP”) and Wex Medical Limited in Hong Kong recorded product revenues of $569,739 for the year ended March 31, 2005, which included generic revenues of $517,997, as compared to $363,764 in the same period in the previous year or an increase of $154,233.  This increase is a result of an expanded generic product line.  The remaining portion of revenue includes the amortization of deferred licensing fees of $284,349 and the $3.1 million (€2 million) relating to the research and collaboration fees from Esteve.

 

All results of operations were in line with management expectations.

 

There have been no material changes during the twelve months ended March 31, 2005 to the forward-looking information provided in the “Management’s Discussion and Analysis of Financial Condition and Operations” for the prior fiscal year.

Corporate Developments

  • The Company advanced its lead drug candidate Tectin™ into a Phase IIb/III trial in Canada for patients suffering from moderate to severe inadequately controlled cancer-related pain.  This trial is ongoing and recruitment and dosing is expected to be completed by the end of June 2006.
  • The Company's wholly owned subsidiary in Hong Kong, Wex Medical Limited, issued unsecured convertible debentures in the aggregate principal amount of US $5.1 million to three investment funds managed by a major Asian financial institution and its affiliates.
  • The Company began a Tectin™ Phase II trial in China for patients suffering from moderate to severe inadequately controlled cancer-related pain.  The first part of the study is now completed and the results are expected in the summer of 2005.
  • The Company along with its European partner held a positive end of Phase IIa meeting with the U.S. Food and Drug Administration ("FDA").  The Company received confirmation that the FDA will accept foreign studies, conducted to International Conference of Harmonization ("ICH") standards, as part of an New Drug Application ("NDA") filing, and is encouraged that its current efforts in Canada and Europe will be an important part of the U.S. commercialization strategy.
  • The Company’s research facilities in China were expanded by 1000 m2 and equipped with state of the art technology to support its many ongoing research projects.  While the primary focus at WEX is on the development of products derived from Tetrodotoxin ("TTX") this year the Company has been evaluating many new compounds derived from natural toxins and has added several early stage products to its pipeline.
  • The Company changed its name from International Wex Technologies Inc. to WEX Pharmaceuticals Inc. which the Company believes better describes its business operations.  The trading symbol on the TSX remains as WXI.
  • The Company initiated a Canadian Phase IIa study on the efficacy and safety of Tetrodin™ alleviating Naloxone-precipitated withdrawal in Methadone maintained subjects.  Results are expected during the summer of 2005. 
  • The Company signed an agreement with Esteve to make certain amendments to the previously executed License and Collaboration Agreement relating to the Company’s products Tectin™, Tetrodin™ and Tocudin™.  The amendments expand the existing collaboration to include additional co-development work.  WEX believes that commercialization of Tectin™ in the most expeditious manner will be achieved by effectively utilizing combined resources.
  • WEX invoiced Esteve in the amount of €2,000,000 (approximately Cdn $3,136,200) for Research and Development work done for the recently completed Tectin™ Phase IIa trial in Canada.  Subsequently, the funds were received in April 2005.
  • During this fiscal year, management further strengthened the Company by hiring 25 new employees, the majority in clinical and scientific research.  Michael Perri joined the Company as Chief Financial Officer and Dr. Jean Bourgouin joined the Company as Chief Medical Officer in charge of all clinical, non-clinical and discovery programs.

About WEX Pharmaceuticals Inc.

WEX Pharmaceuticals Inc. is dedicated to the discovery, development, manufacture and commercialization of innovative drug products to treat moderate to severe acute and chronic pain, symptom pain relief associated with addiction withdrawal from opioid abuse and medicines designed for local anaesthesia.  The Company’s principal business strategy is to derive drugs from naturally occurring toxins and develop proprietary products for the Global market.  The Company’s Chinese subsidiary sells generic products manufactured at its facility in China.

Forward Looking Statements

This News Release contains forward-looking statements which may not be based on historical fact. Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results, events or developments to be materially different from any future results, events or developments expressed or implied by such forward-looking statements.  These factors should be considered carefully and readers are cautioned not to place undue reliance on such forward-looking statements. The company disclaims any obligation to update any such factors or to publicly announce the result of any revisions to any of the forward-looking statements contained herein to reflect future results, events or developments.

For additional information on our products, visit us at www.wexpharma.com or call Don Evans or Gordon Stanley, Corporate Communications at 604-683-8880 or 1-800-722-7549.


WEX PHARMACEUTICALS INC.

(formerly International Wex Technologies Inc.)

Incorporated under the laws of Canada

 

CONSOLIDATED BALANCE SHEETS

 

 

As at March 31

(expressed in Canadian dollars)

 

2005

2004

_____________________________________
_______________
______[Restated(1)]

ASSETS

   

Current

   

Cash and cash equivalents

$

10,233,288

$

    8,301,863

Restricted cash

23,000

232,336

Short-term investments

10,581,176

10,000,000

Accounts and other receivables        

3,716,189

199,083

Investment tax credit receivable

293,000

100,000

Inventories

81,080

38,748

Prepaid expenses, deposits and others______

________447,193

__________884,906

Total current assets

25,374,926

19,756,936

 

 

 

Deposits

125,000

-

Property and equipment

2,802,823

1,556,493

Intangible assets

4,079,145

4,545,332

 

 

 

TOTAL ASSETS 

$

32,381,894

$

  25,858,761

 

 

 

LIABILITIES AND SHAREHOLDERS’ EQUITY

 

 

Current

 

 

Accounts payable and accrued liabilities

$

     3,146,016

$

      818,396

Due to directors

-

99,831

Deferred revenue

187,778

316,540

Capital lease obligations__________________

________27,036_

__________25,629

Total current liabilities

3,360,830

1,260,396

 

 

 

Deferred tenant inducements

214,610

-

Deferred revenue

688,520

844,106

Capital lease obligations

19,386

50,270

Convertible debentures

4,295,419

-

_________________________________ 

______________

________________

Total liabilities

8,578,765

2,154,772

 

 

 

Commitments and contingencies

 

 

 

 

 

Shareholders’ equity

 

 

Share capital

62,583,019

55,161,562

Equity component of convertible debentures

2,332,443

-

Contributed surplus

4,533,117

2,523,216

Deficit________________________________

____(45,645,450)

            (33,980,789)

Total shareholders’ equity

23,803,129

23,703,989

__________________________________ 

________________

_________________

TOTAL LIABILITIES AND SHAREHOLDERS EQUITY

$

32,381,894

$

25,858,761

         

Restated to reflect the change in accounting policy on patents


 

WEX PHARMACEUTICALS INC.

(formerly International Wex Technologies Inc.)

  

CONSOLIDATED STATEMENTS OF
OPERATIONS AND DEFICIT

 

 

Years ended March 31

(expressed in Canadian dollars)

 

____________________________________________________

2005

_____________

2004
________[Restated (1)]

 

 

 

Revenue

 

 

Product sales

$

        569,739

$

 414,764

License fees

284,349

316,540

Research and collaboration fees_____________________

_____3,136,200

____________-

 

3,990,288

731,304

 

 

 

Cost of goods sold - product sales

375,350

249,542

_________________________________________

_____________

____________ 

 

3,614,938

481,762

 

 

 

Expenses

 

 

Research and development

8,635,609

4,259,386

General and administrative

5,217,778

3,748,717

Amortization

796,068

471,647

Total operating expenses 

14,649,455

8,479,750

_______________________________________________

_____________

____________ 

Operating loss___________________________________

___(11,034,517)

___(7,997,988)

 

 

 

Other

 

 

Convertible debentures - interest expense

(559,700)

-

Interest and sundry income

447,403

149,004

Foreign exchange loss_____________________________

_____(517,847)

_____(170,468)

Total other

(630,144)

(21,464)

_______________________________________________ 

_____________ 

____________

Loss for the year

(11,664,661)

(8,019,452)

 

 

 

Deficit, beginning of year_______________________

___(33,980,789)

_(25,961,337)

 

 

 

Deficit, end of year

$

(45,645,450)

$

(33,980,789)

 

 

 

Basic and diluted loss per share

(0.35)

(0.31)

______________________________________________ 

_____________ 

___________ 

Weighted average number of common shares
outstanding

33,591,889

25,697,183

 

(1) Restated to reflect the change in accounting policy on patents


WEX PHARMACEUTICALS INC.

(formerly International Wex Technologies Inc.)

 

 

CONSOLIDATED STATEMENTS OF

CASH FLOWS

 

Years ended March 31

(expressed in Canadian dollars)

 

__________________________________________________

2005

_______________

2004
_______[Restated (1)]

 

 

 

OPERATING ACTIVITIES

 

 

Loss for the year

$   (11,664,661)

$   (8,019,452)

Adjustment for items not involving cash:

 

 

Amortization of capital assets and intangibles

796,068

471,647

amortization of deferred tenant inducement allowance

(25,337)

-

Loss on disposal of property and equipment

14,894

2,086

Stock-based compensation

2,152,721

2,138,063

Accretion of liability component on convertible debentures

527,438

-

Foreign exchange expense on convertible debentures

(429,299)

-

Amortization of deferred financing costs

3,844

-

Amortization of deferred revenue

(284,349)

(316,540)

__________________________________________________ 

(8,908,681)

(5,724,196)

 

 

 

Changes in non-cash working capital items:

 

 

Accounts and other receivables

(3,517,106)

(144,740)

Investment tax credit receivable

(193,000)

26,849

Inventories

(42,332)

10,504

Prepaid expenses, deposits and other

583,149

(55,260)

Accounts payable and accrued liabilities

2,327,621

316,534

_______________________________________ 

_____________ 

____________ 

Cash used in operating activities_________________

____(9,750,349)

____5,570,309)

 

 

 

INVESTING ACTIVITIES

 

 

Purchase of short-term investments

(10,581,176)

(10,023,000)

Proceeds from short-term investments

10,000,000

1,023,000

Rental deposit

(250,000)

-

Tenant inducement allowance received

239,947

-

Restricted cash

209,336

(209,336)

Purchase of property and equipment_______________

____(1,591,104)

_____(999,544)

Cash used in investing activities_______________

____(1,972,997)

__(10,208,880)

 

 

 

FINANCING ACTIVITIES

 

 

Debentures issued, net of issuance costs

6,781,736

-

Proceeds from issuance of share capital, net of issuance costs

7,278,637

23,474,814

Repayment of amounts due to directors

(99,831)

(215,135)

Repayment of capital lease obligations

(29,477)

(22,002)

Convertible debentures - interest repayments_______

______(276,294)

____________-

Cash provided by financing activities_____________

_____13,654,771

____23,237,677

 

 

 

Increase in cash and cash equivalents

1,931,425

7,458,488

 

 

 

Cash and cash equivalents, beginning of year

8,301,863

843,375

 

 

 

Cash and cash equivalents, end of year

$     10,233,288

 $   8,301,863

 

(1) Restated to reflect the change in accounting policy on patents


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