News Release
Confirmed Validation for Drug Product (Tetrodin) and its Drug
Substance
Date: September 7, 2000
CDNX Trading Symbol: WXI
World Wide Web: http://www.wextech.ca
E-mail: wex@wextech.ca
International Wex Technologies Inc. (the "Company") is pleased
to announce that the Company has now received 2 Certificates of
Analysis from a Canadian qualified laboratory. These 2 certificates
validate the Company's Drug Product and Drug Substance both as
to the quality and confirmation of the Chinese standard as
manufactured and provided by our manufacturing subsidiary in China.
The direct benefits to the Company are to reinforce that we have
a good solid foundation on the testing and their results obtained
in China plus provide the needed confidence to independent parties
that are currently reviewing and have reviewed our documentation.
The Drug Product, Tetrodin, is the actual manufactured item that
is administered at its prescribed safe level for humans.
This validation allows the Company to make available a supply
of the finished Drug Product for the start of Clinical trials
in Canada. These trials will occur when the HPB
(Health Protection Branch, Canada) gives permission
for the commencement of Phase 1 trials. Phase 1 trials
can commence after the HPB receives the Company's IND
(Investigational New Drug) application and has approved the
application.
The Drug Substance, TTX, is obtained from the natural raw
material and processed through the Company's unique processing
method and equipment (currently being patented).
This Certificate of Analysis provides the Company the
needed validation to file a drug master file (DMF) with HPB.
An in depth dossier is required for this filing.
Once this documentation has been filed, the Company
can offer to sell the Drug Substance in any purity to
any laboratory, research group, University, etc.; as
a tool for research on the sodium channel blocker.
International Wex Technologies Inc. now has the ability
to produce TTX at a higher purity level and in greater
volume, far exceeding any other known facility in the world.
This report will now form part of the material that will be presented to
the HBP when it meets for its pre-IND meeting in Ottawa on Thursday
August 31, 2000.
Tetrodin(HT) has been developed by the company primarily as a treatment for
the symptoms associated with withdrawal from all opiate addictions such as
morphine, opium, heroin and methadone. It is a non-narcotic pharmaceutical that has
proven to be safe and effective and functions well in both primary withdrawal treatment
and abstinence maintenance (longer term use) of drug addiction. The company has also
begun tests on the usage of Tetrodin(HT) as a potent analgesic.
For additional information on Tetrodin(HT), view the IWT website at
http://www.wextech.ca or call Howard Milne , V. P. Shareholder
Communications, at 604-683-8880 or 1-800-722-7549.
Per: Donna Shum, Corporate Secretary
The Canadian Venture Stock Exchange has not reviewed and does not accept responsibility for the adequacy or accuracy of the content of this News Release.
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